Measuring agreement between cervical vertebrae and hand-wrist maturation in determining skeletal age: reassessing the theory in patients with short stature

Shahla Momeni Danaei; Amirali Karamifar; Ahmadreza Sardarian; Shoaleh Shahidi; Hamdollah Karamifar; Abbas Alipour; Sahar Ghodsi Boushehri

doi:10.1016/j.ajodo.2014.05.023

Measuring agreement between cervical vertebrae and hand-wrist maturation in determining skeletal age: reassessing the theory in patients with short stature

Am J Orthod Dentofacial Orthop. 2014 Sep;146(3):294-8. doi: 10.1016/j.ajodo.2014.05.023.

Authors

Shahla Momeni Danaei¹, Amirali Karamifar², Ahmadreza Sardarian³, Shoaleh Shahidi⁴, Hamdollah Karamifar⁵, Abbas Alipour⁶, Sahar Ghodsi Boushehri⁷

Affiliations

¹ Professor, Orthodontics Research Center, Department of Orthodontics, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
² Assisstant professor, Department of Orthodontics, School of Dentistry, Semnan University of Medical Sciences, Semnan, Iran.
³ Resident, Student Research Committee, Orthodontics Research Center, Department of Orthodontics, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran. Electronic address: sadra.sardarian@yahoo.com.
⁴ Associate professor, Biomaterial Research Center, Department of Radiology, School of Dentistry, Shiraz University of Medical Sciences, Shiraz, Iran.
⁵ Professor, Department of Pediatric Medicine, Endocrinology Division, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.
⁶ Assistant professor, Department of Community Medicine, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.
⁷ Student Research Committee, Shiraz University of Medical Sciences, School of Dentistry, Shiraz, Iran.

PMID: 25172251
DOI: 10.1016/j.ajodo.2014.05.023

Abstract

Introduction: The objective of this study was to determine the degree of agreement between hand-wrist radiography and cervical vertebral maturation analysis in patients diagnosed with short stature.

Methods: A cross-sectional study was designed; 178 patients (90 girls, 88 boys) diagnosed with short stature and seeking treatment were selected. The patients were divided into 2 groups (76 with familial short stature, 102 with nonfamilial short stature). Hand-wrist and lateral cephalometric radiographs were obtained from the patients. The hand-wrist radiographs were analyzed using the Fishman method, and the lateral cephalometric views were categorized according to the method of Hassel and Farman. The degree of agreement between the 2 methods of predicting skeletal maturation was measured by calculating the contingency coefficient and the weighted kappa statistic.

Results: A high degree of agreement was observed between the 2 methods of analyzing skeletal maturation. It was also observed that agreement was higher in girls in the familial short-stature group, whereas boys had higher agreement in the nonfamilial short-stature group.

Conclusions: Cervical vertebral maturation can be a valuable substitute for hand-wrist radiography in patients with short stature.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adolescent
Age Determination by Skeleton / methods*
Age Determination by Skeleton / statistics & numerical data
Body Height / physiology
Bone Development / physiology
Carpal Bones / diagnostic imaging
Carpal Bones / growth & development*
Cephalometry / methods
Cervical Vertebrae / diagnostic imaging
Cervical Vertebrae / growth & development*
Child
Cross-Sectional Studies
Female
Growth Disorders / physiopathology*
Hand Bones / diagnostic imaging
Hand Bones / growth & development*
Humans
Male
Reproducibility of Results
Sex Factors